Newsday reported yesterday on the results of a recent government study investigating the link between hormone replacement therapy and heart disease in middle-aged women.
Like most other news organizations focusing on the report, Newsday highlighted the study’s major findings — specifically, that the use of estrogen for the relief of menopausal symptoms does not increase, and may actually decrease, the risk of heart disease in certain groups of women.
“Postmenopausal estrogen therapy does not appear to protect women in their 60s and older from heart disease,” wrote Newsday staff writer Delthia Ricks, “but researchers say it may have some protective effect for women in their 50s.”
Unlike most other news organizations, Newsday also reported what might seem to be a merely tangential implication of the study — that its findings could affect the warning label on the estrogen replacement drug Premarin.
“Given the new findings, some experts said Food and Drug Administration warnings in package inserts of estrogen pills might be too stringent,” reported Newsday. “The inserts summarize problems such as the higher propensity for blood clots and strokes.”
So who were these “experts” calling for a revised FDA warning on the estrogen drug Premarin?
The story cites only one. That would be Dr. Lila Nachtigall, who told Newsday, “One of the things that’s frightening to doctors is to have this package insert. And, of course, for the patient it is frightening to read that warning.”
We’re can’t say for certain whether the FDA’s Premarin warning is appropriate or not, but we’d definitely attach a strongly worded warning to any story containing a quote from Dr. Nachtigall. It would be something subtle, like:
WARNING!!! DR. NACHTIGALL HAS BEEN PAID BY A PHARMACEUTICAL COMPANY THAT MAKES BILLIONS OF DOLLARS SELLING ESTROGEN PILLS. TAKE WITH GLASS OF WATER, AND GRAIN OF SALT.
Newsday identified Dr. Nachtigall as “a professor of obstetrics and gynecology at New York University Medical Center.” The reporter neglected to mention that (a) Dr. Nachtigall co-authored Estrogen: The Facts Can Change Your Life, a book of unrivalled estrogen-replacement-therapy boosterism, and (b) according to the disclosures section on the Web Site for the Council on Hormone Education, she receives a honoraria from Wyeth Pharmaceuticals. That would be the same Wyeth Pharmaceuticals that manufactures Premarin.
Not that Dr. Nachtigall’s conflict-of-interest should come as much of a surprise.
Back in 2002, CBS News ran an investigative piece called “Hormone Hype” in which correspondent Sharyl Attkisson honed in on the unsavory relationship between doctors who advocate for hormone replacement therapy (HRT) and the pharmaceutical companies that profit from it.
“The selling of HRT was a coup by any standard, generating $3 billion a year,” reported Attkisson. “One news magazine even called it the closest thing to putting youth in a tablet. But a lot of the claims weren’t backed by serious science. And women never knew the same doctors promoting the wonders of HRT often had financial ties to the drugmakers.”
Enter Dr. Nachtigall.
“For years, much of that [grossly exaggerated] information got into print, bolstered by quotes from respected experts on the cutting edge of hormone research, like Dr. Lila Nachtigall,” noted Attkisson. “She questioned the breast cancer link and touted bonuses, like the supposed heart benefit, good looks and great sex. Readers weren’t told Nachtigall also gets paid to speak for at least 11 drug companies, including Wyeth, the biggest maker of HRT drugs.”
Four years later, Newsday still isn’t telling its readers about Dr. Nachtigall’s potential conflict of interest, which is too bad. After all, newspaper readers, like pill poppers, should know what they are digesting.

There are many reasons to rant about how the MSM report on women's health issues. I haven't written anything lately, but I did critique the original Women's Health Initiative reporting.
The fact is that Wyeth underwrote the WHI study and the ONLY drug tested was Premarin and PremPro. No one has tested -- at least in the US -- alternative supplemental hormone therapy (replacment therapy for thoses of us who lost our ovaries "prematurely" due to hysterectomies).
However, that does not, in an of itself, discount the validity of the research so long as media frame it as research on Wyeth drugs, not all estrogen (which is how all news stores have been framed).
I had a far bigger grievance with the MSM reporting: most headlines contradicted the main part of the story -- based on the bias evident in the lead graph. Contrary to the "it doesn't help" meme, the research showed that even conjugated-equine-estrogen helped prevent hip fractures for one sub-group. The bigger question remains: who the devil approved a study designed to test supplemental estrogen (or estrogen replacement, in the case of part 2) where the median age of the women *starting* the drug was in the 60s? It is SO flawed methodologically, because it bears almost zero relation to when women are likely to start taking some form of estrogen. [Some think it's because women in the throes of menopause were/would be unwilling to participate in a long-term study where they might get a placebo and thus have no relief from menopausal complications.)
BTW, you failed to note that the "disclaimers" associated with Council on Hormone Education show that they are ALL associated with Wyeth.
Posted by kathy gill on Mon 20 Feb 2006 at 02:24 PM
MAXIDEX WARNING
I had eye surgery and in the post-op pack was MAXIDEX(dexamethasone) drops by ALCON LABS.
Two days later I was BLIND
Use Google and enter EPOCRATES MAXIDEX to verify
Package insert reads :change in vision"
Posted by WEL on Fri 22 Aug 2008 at 04:51 PM