Laurel to the Baltimore Sun for spotlighting abuse and street sales of buprenorphine, a widely hailed prescription drug for treating opiate addiction, in a series of well-reported articles published late last year. And a mini-dart to the same series for ultimately failing to put the “bupe” problem in proper context (see Editor’s Note, page 9).

As the Sun explained, bupe is a significant advance over methadone, the long-dominant treatment for heroin and painkiller addiction. Methadone provides a stronger high than bupe and can be fatal in an overdose. Suboxone, an FDA-approved form of buprenorphine, forestalls euphoria past a certain dosage and contains an agent, naloxone, intended to trigger withdrawal symptoms when crushed and injected. Most coverage of buprenorphine has touted the drug’s resistance to abuse and its proven effectiveness in combating addiction. The Sun’s three-part series and follow-up articles brought important balance to the bupe story by vigorously raising the issue of street sales and the specter of addicts using “street chemistry” to subvert naloxone to achieve an opiate high.

Reporters Doug Donovan, Fred Schulte, and Erika Niedowski hit the streets to document abuse and diversion in West Baltimore, New England, and France. They discovered that little data exist on bupe’s role in overdose deaths because many medical examiners have no way to detect traces of the drug. The street reporting was the story’s strength. Much of the enthusiasm over buprenorphine is based on its success in research settings, but the reporters searched out patients, doctors, and medical examiners to chronicle its effects in the real world.

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